Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 4/20 | 0.32 |
| ▸ | HTR7 | P34969 | 4/20 | 0.32 |
| ▸ | HTR6 | P50406 | 4/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718329 | 0.90 | ALDH1A1 (0.33) | ALDH1A1KDM4EHPGDCYP3A4GAA | |
| Hydrochloric Acid SCHEMBL7872294 | 0.89 | ALDH1A1 (0.33) | ALDH1A1KDM4EHPGDCYP3A4GAA | |
| SCHEMBL8713635 | 0.85 | ALDH1A1 (0.33) | ALDH1A1KDM4EHPGDCYP3A4GAA | |
| SCHEMBL7871653 | 0.83 | PDE5A (0.37) | ALDH1A1KDM4EHPGDCYP3A4GAA | |
| Hydrochloric Acid SCHEMBL7872363 | 0.83 | PDE5A (0.36) | ALDH1A1KDM4EHPGDCYP3A4GAA | |
| SCHEMBL8713347 | 0.82 | HTR1A (0.34) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL7870297 | 0.76 | HTR2A (0.33) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL8712584 | 0.76 | ALDH1A1 (0.32) | ALDH1A1KDM4EHPGDCYP3A4GAA | |
| SCHEMBL8701072 | 0.75 | HTR7 (0.36) | RORCHTR1ADRD2HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL7872413 | 0.75 | HTR7 (0.33) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826686-A2 | Tricyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |