Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9033421 | 0.83 | SMN1; SMN2 (0.41) | HRH3ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8697846 | 0.79 | OPRK1 (0.44) | HRH3TSHRSMN1; SMN2 | |
| SCHEMBL8703407 | 0.78 | HRH3 (0.39) | SIGMAR1HRH3LTA4HALDH1A1 | |
| SCHEMBL8702811 | 0.74 | HRH3 (0.40) | SIGMAR1HRH3LTA4HTSHRALDH1A1 | |
| SCHEMBL9033216 | 0.74 | ALDH1A1 (0.40) | HRH3TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9031813 | 0.73 | HRH3 (0.41) | HRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL8698602 | 0.73 | HRH3 (0.38) | SIGMAR1HRH3LTA4HALDH1A1SLC6A3 | |
| SCHEMBL8697765 | 0.73 | HRH3 (0.43) | HRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL9035119 | 0.72 | HRH3 (0.39) | HRH3ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9034272 | 0.70 | ATM (0.45) | HRH3TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834460-A | FOR TREATMENT OF BRAIN OR PSYCHOLOGICAL DISORDERS, ALZHEIMER*S DISEASE, MENTAL RETARDATION OR AUTISM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |