Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTR1E | P28566 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244317 | 0.76 | OPRM1 (0.43) | PKMADORA2BALDH1A1KMT2ATSHR | |
| SCHEMBL8704429 | 0.76 | KDM4E (0.35) | ALDH1A1TSHRKDM4EHSD17B10OPRM1 | |
| SCHEMBL8701089 | 0.66 | OPRM1 (0.31) | OPRM1 | |
| SCHEMBL1428238 | 0.65 | OPRM1 (0.44) | ALDH1A1LMNAKDM4EMAPTTP53 | |
| SCHEMBL7415776 | 0.65 | CHRM3 (0.51) | TSHRLMNATP53OPRM1SMN1; SMN2 | |
| SCHEMBL4861464 | 0.64 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAKDM4EHPGD | |
| SCHEMBL7421543 | 0.64 | OPRM1 (0.47) | LMNAHSD17B10TP53OPRM1SMN1; SMN2 | |
| SCHEMBL1428246 | 0.64 | CHRM3 (0.53) | TSHRLMNATP53OPRM1SMN1; SMN2 | |
| SCHEMBL7414392 | 0.64 | CHRM3 (0.53) | TSHRLMNATP53OPRM1SMN1; SMN2 | |
| SCHEMBL7425414 | 0.62 | TP53 (0.58) | ALDH1A1KMT2ALMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789415-A | Azacyclic-heterocyclic compounds as angiotension II receptor antagonists | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |