Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701411 | 0.86 | TACR3 (0.47) | MAPTMEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL9016350 | 0.82 | SMN1; SMN2 (0.41) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8705983 | 0.81 | MAPT (0.57) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8699355 | 0.77 | CHRM4 (0.45) | MAPTMEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL6652670 | 0.76 | PHGDH (0.58) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8701406 | 0.76 | KMT2A (0.64) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8704504 | 0.75 | MAPT (0.54) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL6963593 | 0.75 | MAPT (0.54) | MAPTKMT2AALDH1A1HSD17B10GAA | |
| SCHEMBL8704176 | 0.75 | MAPT (0.55) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8699278 | 0.74 | KMT2A (0.42) | MAPTMEN1KMT2AALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |