Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 2/20 | 0.47 |
| ▸ | RBP4 | P02753 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699355 | 0.90 | CHRM4 (0.45) | RBP4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8701100 | 0.86 | MAPT (0.39) | TACR3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8705983 | 0.85 | MAPT (0.57) | RBP4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8700086 | 0.83 | RBP4 (0.47) | RBP4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8701406 | 0.80 | KMT2A (0.64) | MEN1KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL6963593 | 0.79 | MAPT (0.54) | RBP4KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL8704176 | 0.79 | MAPT (0.55) | RBP4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8704504 | 0.79 | MAPT (0.54) | RBP4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6652670 | 0.79 | PHGDH (0.58) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL9057833 | 0.79 | RBP4 (0.50) | RBP4MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |