Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 3/20 | 0.45 |
| ▸ | RBP4 | P02753 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.43 |
| ▸ | PRKG1 | Q13976 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701411 | 0.90 | TACR3 (0.47) | RBP4ROCK2PRKG1MAPTKMT2A | |
| SCHEMBL8704636 | 0.86 | KMT2A (0.57) | RBP4CYP1A2MAPTKMT2ANPSR1 | |
| SCHEMBL8700086 | 0.83 | RBP4 (0.47) | CHRM4RBP4ROCK2PRKG1LIMK2 | |
| SCHEMBL8699351 | 0.80 | ALDH1A1 (0.66) | CYP1A2MAPTKMT2ANPSR1ALDH1A1 | |
| SCHEMBL8701044 | 0.79 | KMT2A (0.65) | CYP1A2MAPTKMT2ANPSR1ALDH1A1 | |
| SCHEMBL8702850 | 0.78 | PANK3 (0.56) | MAPTKMT2ANPSR1ALDH1A1LMNA | |
| SCHEMBL8701100 | 0.77 | MAPT (0.39) | MAPTKMT2AALDH1A1LMNATSHR | |
| SCHEMBL8705064 | 0.76 | HTR1A (0.52) | RBP4MAPTKMT2ANPSR1ALDH1A1 | |
| SCHEMBL8699098 | 0.76 | PANK3 (0.54) | RBP4CYP1A2MAPTKMT2ANPSR1 | |
| SCHEMBL8704639 | 0.76 | ALDH1A1 (0.40) | CYP1A2MAPTKMT2ANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |