Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705983 | 0.83 | MAPT (0.57) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL8701100 | 0.82 | MAPT (0.39) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL8704718 | 0.79 | FAAH (0.49) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL8699278 | 0.79 | KMT2A (0.42) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL9057833 | 0.78 | RBP4 (0.50) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL6963593 | 0.77 | MAPT (0.54) | KMT2AKDM4EMAPTPKMRAB9A | |
| SCHEMBL8704176 | 0.77 | MAPT (0.55) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL8704504 | 0.77 | MAPT (0.54) | MEN1KMT2AL3MBTL1KDM4EMAPT | |
| SCHEMBL9057732 | 0.77 | FAAH (0.54) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL8705064 | 0.77 | HTR1A (0.52) | SMN1; SMN2KMT2AKDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |