SCHEMBL8701143

SCHEMBL8701143

Cc1ccc(C(C)(C)C)c(O[SiH](c2ccccc2)c2ccccc2)c1CO

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8849626 0.72 CYP1A2 (0.33)
SCHEMBL5232516 0.71 MAPT (0.37) GAA
SCHEMBL7994314 0.69 CYP1A2 (0.34) ALDH1A1GAA
SCHEMBL10848334 0.69
SCHEMBL5766596 0.67 GLRA3 (0.36) ALDH1A1GAA
SCHEMBL10245825 0.67 GABRA1 (0.48) ALDH1A1
SCHEMBL704146 0.65 ALDH1A1 (0.43) ALDH1A1GAA
SCHEMBL5766157 0.65 ALDH1A1 (0.32) ALDH1A1
SCHEMBL7779658 0.65 KDM4E (0.32) ALDH1A1GAA
SCHEMBL17307162 0.65 GABRA1 (0.55) ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5827868-A Prostaglandin analogs E. R. SQUIBB & SONS, INC. (US) 1998-10-27 US disclosed