Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.36 |
| ▸ | GLRB | P48167 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | JUN | P05412 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5766157 | 0.84 | ALDH1A1 (0.32) | ALDH1A1TNFRSF1A | |
| SCHEMBL5766593 | 0.78 | RXRA (0.34) | GAAKDM4ERXRARXRBRXRG | |
| SCHEMBL1651927 | 0.69 | CA1 (0.46) | ALDH1A1GAAKDM4ETNFRSF1ACYP2C19 | |
| SCHEMBL8701143 | 0.67 | ALDH1A1 (0.32) | ALDH1A1GAA | |
| SCHEMBL5232516 | 0.66 | MAPT (0.37) | GAARXRARXRBRXRGTNFRSF1A | |
| SCHEMBL25288785 | 0.63 | KDM4E (0.34) | KDM4ERARARARBRARGTNFRSF1A | |
| SCHEMBL5236562 | 0.63 | CA1 (0.40) | ALDH1A1GAAKDM4ERARARARB | |
| SCHEMBL5235408 | 0.63 | RXRA (0.31) | RXRARXRBRXRG | |
| SCHEMBL19194020 | 0.62 | GLRA3 (0.68) | GLRA3GLRBALDH1A1GAAKDM4E | |
| SCHEMBL10848334 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315732-B1 | RADICICOL AND MONOCILLIN AND THEIR ANALOGUES AND USES THEREOF | SLOAN KETTERING INST CANCER (US) | 2006-06-07 | — | — | EP | disclosed |
| US-20020091151-A1 | Novel macrocycles and uses thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2002-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091151-A1 | Novel macrocycles and uses thereof | ABCE1, DCK, BDKRB1 | GLRA3 502/4885GLRB 300/4885ALDH1A1 1572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.