Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | MAT2A | P31153 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | BID | P55957 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460900 | 0.86 | CMA1 (0.58) | TDP1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL8707152 | 0.78 | MAT2A (0.43) | TDP1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL3783551 | 0.72 | CMA1 (0.69) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7464976 | 0.71 | CMA1 (0.53) | KMT2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7466245 | 0.70 | CMA1 (0.60) | TDP1KMT2ACMA1MAPTMCL1 | |
| SCHEMBL3786281 | 0.69 | CMA1 (0.64) | CMA1MAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL8706895 | 0.69 | MEN1 (0.41) | KMT2AMAPTCYP1A2CYP2C19MAT2A | |
| SCHEMBL3786870 | 0.66 | CMA1 (0.53) | CMA1MAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL7465314 | 0.65 | CMA1 (0.71) | KMT2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8706870 | 0.64 | MAT2A (0.36) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |