SCHEMBL3111027

SCHEMBL3111027

Nc1c(CO)ccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 9/20 0.62
KMT2A Q03164 9/20 0.62
ALDH1A1 P00352 6/20 0.62
MAPK1 P28482 6/20 0.62
MAPT P10636 6/20 0.62
POLB P06746 4/20 0.62
L3MBTL1 Q9Y468 3/20 0.62
MCL1 Q07820 3/20 0.62
TDP1 Q9NUW8 3/20 0.62
LMNA P02545 2/20 0.62
THRB P10828 2/20 0.62
PKM P14618 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
MAOA P21397 4/20 0.61
MAOB P27338 1/20 0.61
SMN1; SMN2 Q16637 5/20 0.57
CYP3A4 P08684 3/20 0.57
NPC1 O15118 3/20 0.57
RAB9A P51151 3/20 0.57
TSHR P16473 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16145028 0.87 ALDH1A1 (0.58) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL6682201 0.84 MAPK1 (0.64) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL8359453 0.84 MEN1 (0.55) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL14353222 0.81 MAOA (0.59) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL3991531 0.81 MAOA (0.59) MEN1KMT2AALDH1A1MAPK1MAPT
Digiferruginol SCHEMBL23199057 0.81 ELANE (0.69) MEN1KMT2AALDH1A1MAPK1MAPT
Digiferruginol SCHEMBL30614617 0.81 ELANE (0.69) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL2398142 0.79 ELANE (0.50) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL2396651 0.79 ELANE (0.53) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL2396782 0.79 ELANE (0.50) MEN1KMT2AALDH1A1MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2170307-A2 INHIBITION OF AGE FORMATION BASF Beauty Care Solutions France SAS (FR) 2010-04-07 EP claimed
CN-101686954-A The inhibition that AGE forms BASF BEAUTY CARE SOLUTIONS F 2010-03-31 CN claimed
WO-2009007411-A2 INHIBITION OF AGE FORMATION BASF BEAUTY CARE SOLUTIONS FRANCE SAS (FR) 2009-01-15 WO claimed
CN-115025129-B Composition containing lactobacillus and use thereof for preventing and/or improving skin aging 葡萄王生技股份有限公司 2024-04-19 CN disclosed
EP-3342396-B1 EXTERNAL PREPARATION FOR SKIN FOR REDUCING SKIN YELLOWNESS HAYASHIBARA CO (JP) 2023-04-12 EP disclosed
CN-115025129-A Lactobacillus-containing composition and application thereof in preventing and/or improving skin aging 葡萄王生技股份有限公司 2022-09-09 CN disclosed
CN-107920981-B Skin external preparation for reducing dark yellow 株式会社林原 2021-06-08 CN disclosed
EP-3398585-B1 EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME HAYASHIBARA CO (JP) 2020-02-26 EP disclosed
US-10568827-B2 External dermal agent for reducing yellowish dullness Hayashibara Co., Ltd. (JP) 2020-02-25 US disclosed
US-20190008747-A1 EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME Hayashibara Co., Ltd. (JP) 2019-01-10 US disclosed
CN-105585601-B Anti-aging skin external composition and preparation method thereof 株式会社林原 2018-11-13 CN disclosed
US-20130078202-A1 INHIBITION OF THE FORMATION OF AGEs BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) 2013-03-28 US disclosed
US-20100316743-A1 INHIBITION OF THE FORMATION OF AGEs BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) 2010-12-16 US disclosed
US-20100203175-A1 DEGLYCATION OF AGEs BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) 2010-08-12 US disclosed
CN-101765432-A AGE deglycation BASF BEAUTY CARE SOLUTIONS F 2010-06-30 CN disclosed
EP-2170358-A2 AGE DEGLYCATION. BASF Beauty Care Solutions France SAS (FR) 2010-04-07 EP disclosed
EP-2170307-A2 INHIBITION OF AGE FORMATION BASF Beauty Care Solutions France SAS (FR) 2010-04-07 EP disclosed
CN-101686954-A The inhibition that AGE forms BASF BEAUTY CARE SOLUTIONS F 2010-03-31 CN disclosed
WO-2009007411-A2 INHIBITION OF AGE FORMATION BASF BEAUTY CARE SOLUTIONS FRANCE SAS (FR) 2009-01-15 WO disclosed
WO-2009007412-A2 AGE DEGLYCATION BASF BEAUTY CARE SOLUTIONS FRANCE SAS (FR) 2009-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100316743-A1 INHIBITION OF THE FORMATION OF AGEs AGER, GLA, S100A6 MEN1 2572/4885KMT2A 3739/4885ALDH1A1 1259/4885
US-20130078202-A1 INHIBITION OF THE FORMATION OF AGEs AGER, GLA, S100A6 MEN1 2572/4885KMT2A 3739/4885ALDH1A1 1259/4885
US-10568827-B2 External dermal agent for reducing yellowish dullness FUT5, ENGASE, FUT6 MEN1 4298/4885KMT2A 1445/4885ALDH1A1 580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.