Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9083341 | 0.89 | FDPS (0.79) | FDPSCYP2D6MEN1LMNATP53 | |
| SCHEMBL9083338 | 0.82 | FDPS (0.70) | FDPSCYP2D6MEN1LMNATP53 | |
| SCHEMBL4105304 | 0.79 | FDPS (0.65) | FDPSCYP2D6MEN1LMNATP53 | |
| SCHEMBL8713222 | 0.78 | FDPS (0.64) | FDPSCYP2D6MEN1LMNATP53 | |
| Perhexiline SCHEMBL4316882 | 0.77 | CYP2D6 (0.80) | FDPSCYP2D6MEN1LMNATP53 | |
| SCHEMBL8778238 | 0.71 | FDPS (0.56) | FDPS | |
| SCHEMBL8648798 | 0.71 | FDPS (0.55) | FDPSCYP2D6MEN1LMNATP53 | |
| SCHEMBL18230965 | 0.71 | FDPS (0.55) | FDPSGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL456091 | 0.71 | CYP2D6 (0.55) | FDPSCYP2D6MEN1LMNATP53 | |
| SCHEMBL21064561 | 0.71 | CYP2D6 (0.55) | FDPSCYP2D6MEN1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608322-B1 | ENHANCED SKIN PENETRATION SYSTEM FOR IMPROVED TOPICAL DELIVERY OF DRUGS | RICHARDSON VICKS INC (US) | 1998-07-22 | — | — | EP | claimed |
| US-5773023-A | BLEND OF AQUEOUS CARRIER, ACTIVE MATERIAL AND POLYACRYLAMIDE | RICHARDSON-VICKS INC. (US) | 1998-06-30 | — | — | US | claimed |
| EP-0608320-B1 | ENHANCED SKIN PENETRATION SYSTEM FOR IMPROVED TOPICAL DELIVERY OF DRUGS | RICHARDSON VICKS INC (US) | 1998-01-28 | — | — | EP | claimed |
| EP-0652774-B1 | PHARMACEUTICAL COMPOSITION FOR TOPICAL USE CONTAINING A CROSSLINKED CATIONIC POLYMER AND AN ALKOXYLATED ETHER | PROCTER & GAMBLE (US) | 1997-05-07 | — | — | EP | claimed |
| US-5614178-A | TRANSDERMAL | THE PROCTER & GAMBLE COMPANY (US) | 1997-03-25 | — | — | US | claimed |
| EP-0652774-A1 | PHARMACEUTICAL COMPOSITION FOR TOPICAL USE CONTAINING A CROSSLINKED CATIONIC POLYMER AND AN ALKOXYLATED ETHER. | PROCTER & GAMBLE (US) | 1995-05-17 | — | — | EP | claimed |
| EP-0608322-A1 | ENHANCED SKIN PENETRATION SYSTEM FOR IMPROVED TOPICAL DELIVERY OF DRUGS | RICHARDSON-VICKS, INC. (US) | 1994-08-03 | — | — | EP | claimed |
| EP-0608320-A1 | ENHANCED SKIN PENETRATION SYSTEM FOR IMPROVED TOPICAL DELIVERY OF DRUGS | RICHARDSON-VICKS, INC. (US) | 1994-08-03 | — | — | EP | claimed |
| EP-0274158-B1 | Novel heterocycle-substituted diphosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate matabolism | NORWICH EATON PHARMA (US) | 1994-03-23 | — | — | EP | claimed |
| WO-1994002176-A1 | PHARMACEUTICAL COMPOSITION FOR TOPICAL USE CONTAINING A CROSSLINKED CATIONIC POLYMER AND AN ALKOXYLATED ETHER | THE PROCTER & GAMBLE COMPANY (US) | 1994-02-03 | — | — | WO | claimed |
| WO-1993007902-A1 | ENHANCED SKIN PENETRATION SYSTEM FOR IMPROVED TOPICAL DELIVERY OF DRUGS | RICHARDSON-VICKS, INC. (US) | 1993-04-29 | — | — | WO | claimed |
| WO-1993007903-A1 | ENHANCED SKIN PENETRATION SYSTEM FOR IMPROVED TOPICAL DELIVERY OF DRUGS | RICHARDSON-VICKS, INC. (US) | 1993-04-29 | — | — | WO | claimed |
| US-5519013-A | Heterocycle-substituted diphosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism | THE PROCTER & GAMBLE COMPANY (US) | 1996-05-21 | — | — | US | disclosed |
| US-5334586-A | Heterocycle-substituted diphosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism | PROCTER & GAMPLE PHARMACEUTICALS, INC. (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0274158-B1 | Novel heterocycle-substituted diphosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate matabolism | NORWICH EATON PHARMA (US) | 1994-03-23 | — | — | EP | disclosed |
| EP-0586521-A1 | CALCIUM, TRACE MINERAL, VITAMIN D AND DRUG THERAPY COMBINATIONS | THE PROCTER & GAMBLE COMPANY (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021355-A1 | CALCIUM, TRACE MINERAL, VITAMIN D AND DRUG THERAPY COMBINATIONS | THE PROCTER & GAMBLE COMPANY (US) | 1992-12-10 | — | — | WO | disclosed |
| US-5071840-A | Certain heterocyclic substituted diphosphonate compounds pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0351897-A2 | Skin penetration system for salts of amine-functional drugs | THE PROCTER & GAMBLE COMPANY (US) | 1990-01-24 | — | — | EP | disclosed |