Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 9/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696336 | 0.83 | HMOX1 (0.47) | TBXAS1KMT2AMEN1 | |
| SCHEMBL8696869 | 0.82 | TP53 (0.46) | TBXAS1KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL8542041 | 0.81 | CYP19A1 (0.45) | TBXAS1 | |
| SCHEMBL8698471 | 0.80 | HMOX1 (0.46) | TBXAS1 | |
| Hydrochloric Acid SCHEMBL8698587 | 0.80 | TBXAS1 (0.46) | TBXAS1 | |
| SCHEMBL8696858 | 0.78 | TBXAS1 (0.55) | TBXAS1KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL8698078 | 0.78 | CYP19A1 (0.50) | TBXAS1 | |
| SCHEMBL8540883 | 0.78 | TBXAS1 (0.65) | TBXAS1LTA4HKMT2AKDM4EALDH1A1 | |
| SCHEMBL10370478 | 0.78 | TBXAS1 (1.00) | TBXAS1LTA4HKMT2AKDM4EALDH1A1 | |
| SCHEMBL8699135 | 0.77 | TBXAS1 (0.58) | TBXAS1KMT2AKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |