Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CIT | O14578 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695080 | 0.94 | MLYCD (0.41) | MLYCDKDM4ELTB4R2ROCK2ROCK1 | |
| SCHEMBL8695261 | 0.93 | ALOX5 (0.45) | MLYCDKDM4ELTB4R2GAAALOX5 | |
| SCHEMBL8698422 | 0.87 | MLYCD (0.35) | MLYCDKDM4ELTB4R2HPGDROCK2 | |
| SCHEMBL8701530 | 0.82 | CDK4 (0.48) | KDM4EKMT2AGAAMEN1LMNA | |
| SCHEMBL8698319 | 0.81 | CIT (0.34) | KMT2ALTB4R2ROCK2ROCK1MEN1 | |
| SCHEMBL2974138 | 0.79 | AGTR1 (0.46) | KMT2ALTB4R2GAAMEN1HTT | |
| SCHEMBL9709582 | 0.78 | IAPP (0.39) | LTB4R2L3MBTL1AGTR1 | |
| SCHEMBL9709552 | 0.77 | IAPP (0.40) | LTB4R2AGTR1 | |
| SCHEMBL443484 | 0.77 | LTB4R2 (0.47) | LTB4R2AGTR1 | |
| SCHEMBL8699095 | 0.77 | MLYCD (0.64) | MLYCDKDM4EKMT2AGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | claimed |
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |