Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701530 | 0.82 | CDK4 (0.48) | KMT2AMEN1GFERLMNASMN1; SMN2 | |
| SCHEMBL8696236 | 0.80 | LMNA (0.66) | KMT2AMEN1NPSR1GFERPOLB | |
| SCHEMBL4609709 | 0.79 | LTB4R2 (0.60) | KMT2AMEN1POLBHPGDALDH1A1 | |
| SCHEMBL9421652 | 0.78 | AOC3 (0.43) | KMT2AMEN1LMNAHPGDALDH1A1 | |
| SCHEMBL6484182 | 0.78 | MMP1 (0.50) | MAPTGAAHTT | |
| SCHEMBL8792800 | 0.78 | CDK4 (0.43) | KMT2AMEN1NPSR1GFERLMNA | |
| SCHEMBL7838803 | 0.78 | LMNA (0.76) | KMT2AMEN1NPSR1GFERPOLB | |
| SCHEMBL6495989 | 0.78 | MAPT (0.45) | MAPTGAAHTT | |
| SCHEMBL6491342 | 0.77 | GHSR (0.53) | MAPTGAAHTT | |
| SCHEMBL8792189 | 0.77 | GHSR (0.53) | MAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | claimed |