Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 2/20 | 0.34 |
| ▸ | FNTB | P49356 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699621 | 0.77 | MAPT (0.43) | MEN1KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL7662936 | 0.73 | MMP2 (0.37) | KMT2AALDH1A1LMNA | |
| SCHEMBL8209492 | 0.66 | CTSD (0.37) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL7061778 | 0.66 | SLC6A3 (0.43) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL29161410 | 0.65 | KDM4E (0.40) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL980483 | 0.65 | MAPT (0.39) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL31616911 | 0.65 | MAPT (0.43) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL542713 | 0.65 | PTGER3 (0.49) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL15413549 | 0.65 | MAPT (0.43) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL28240863 | 0.64 | MEN1 (0.53) | MEN1KMT2AMAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712312-A | MELATONINERGIC RECEPTOR LIGANDS, TREATMENT OF SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1998-01-27 | — | — | US | disclosed |