Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8209492 | 0.84 | CTSD (0.37) | BACE1ALDH1A1BACE2HSD11B1LMNA | |
| SCHEMBL6827479 | 0.78 | BACE1 (0.43) | MMP2MMP9BACE1BACE2REN | |
| SCHEMBL3969972 | 0.78 | BACE1 (0.33) | MMP2MMP9BACE1ALDH1A1BACE2 | |
| SCHEMBL509095 | 0.76 | CYP1A2 (0.33) | MMP2MMP9BACE1ALDH1A1BACE2 | |
| SCHEMBL8701537 | 0.73 | MEN1 (0.41) | ALDH1A1LMNAKMT2A | |
| SCHEMBL11245064 | 0.72 | LMNA (0.38) | MMP2MMP9BACE1ALDH1A1BACE2 | |
| SCHEMBL7272506 | 0.69 | ELANE (0.40) | MMP2MMP9BACE1ALDH1A1CYP2C9 | |
| SCHEMBL7219255 | 0.69 | ELANE (0.40) | MMP2MMP9BACE1ALDH1A1CYP2C9 | |
| SCHEMBL8627083 | 0.68 | — | — | |
| SCHEMBL28548234 | 0.66 | HCAR2 (0.53) | MMP2MMP9ALDH1A1HSD11B1HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344564-B1 | FUNGICIDES | RHONE-POULENC, INC. | 2002-02-05 | — | — | US | disclosed |
| US-6018052-A | APPLYING TO CROPS OR THEIR SEEDS TO PREVENT OR CURE FUNGAL DISEASES; STEREOSPECIFIC COMPOUND WITH IMPROVED BIOLOGICAL ACTIVITY | RHONE-POULENC AGROCHIMIE (FR) | 2000-01-25 | — | — | US | disclosed |
| US-6008370-A | FUNGICIDAL IMIDAZOLINONE AND IMIDAZOLINETHIONE COMPOUNDS FOR USE IN PLANT PROTECTION | RHONE-POULENC AGROCHIMIE (FR) | 1999-12-28 | — | — | US | disclosed |
| US-6002016-A | Fungicidal 2-imidazolin-5-ones and 2-imidazoline-5-thiones | RHONE-POULENC AGROCHIMIE (FR) | 1999-12-14 | — | — | US | disclosed |
| US-5650519-A | Optically active 5, 5-disubstituted-3-(mono- or disubstituted amino)-2-thiohydantoin intermediates to fungicidal 2-imidazolin-5-ones | RHONE-POULENC AGROCHIMIE (FR) | 1997-07-22 | — | — | US | disclosed |
| US-5637729-A | AGRICULTURE | RHONE-POULENC AGROCHIMIE (FR) | 1997-06-10 | — | — | US | disclosed |
| EP-0648210-A1 | FUNGICIDAL 2-IMIDAZOLINE-5-ONE AND 2-IMIDAZOLINE-5-THIONE DERIVATIVES | RHONE-POULENC AGROCHIMIE (FR) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994001410-A1 | FUNGICIDAL 2-IMIDAZOLINE-5-ONE AND 2-IMIDAZOLINE-5-THIONE DERIVATIVES | RHONE POULENC AGROCHIMIE (FR) | 1994-01-20 | — | — | WO | disclosed |