Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701885 | 0.83 | ALDH1A1 (0.42) | L3MBTL1MEN1KMT2ASIGMAR1SMN1; SMN2 | |
| SCHEMBL8703579 | 0.71 | ALOX15 (0.45) | HRH3SMN1; SMN2ALDH1A1 | |
| SCHEMBL11907724 | 0.69 | L3MBTL1 (0.67) | L3MBTL1CYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL11925520 | 0.68 | L3MBTL1 (1.00) | L3MBTL1CYP2D6MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7312043 | 0.68 | L3MBTL1 (0.51) | L3MBTL1CYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL11908467 | 0.66 | L3MBTL1 (0.96) | L3MBTL1CYP2D6MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11499173 | 0.64 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL9279775 | 0.62 | HRH3 (0.54) | L3MBTL1CYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL4247408 | 0.61 | CYP1A2 (0.43) | L3MBTL1CYP1A2CYP3A4CYP2D6HRH3 | |
| SCHEMBL1854770 | 0.61 | CYP1A2 (0.43) | L3MBTL1CYP1A2CYP3A4HRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773456-A | EMPHYSEMA, RHEUMATOID ARTHRITIS AND PANCREATITIS | SANOFI (FR) | 1998-06-30 | — | — | US | disclosed |