Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701713 | 0.83 | L3MBTL1 (0.51) | ALDH1A1SIGMAR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16982100 | 0.73 | LTA4H (0.42) | ALDH1A1SIGMAR1MAPK1HSD17B10CNR1 | |
| SCHEMBL8706167 | 0.73 | ALDH1A1 (0.42) | ALDH1A1MAPK1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL1779278 | 0.71 | LTA4H (0.42) | ALDH1A1SIGMAR1CNR1POLBHTT | |
| SCHEMBL3176062 | 0.71 | ADORA2A (0.41) | ALDH1A1SIGMAR1HSD17B10POLBSMN1; SMN2 | |
| SCHEMBL12263487 | 0.70 | MAPK1 (0.49) | ALDH1A1SIGMAR1MAPK1HSD17B10POLB | |
| SCHEMBL7308113 | 0.70 | SIGMAR1 (0.41) | ALDH1A1SIGMAR1MAPK1HSD17B10CNR1 | |
| SCHEMBL2400051 | 0.70 | L3MBTL1 (0.71) | ALDH1A1MAPK1HSD17B10POLBSMN1; SMN2 | |
| SCHEMBL8814161 | 0.67 | ALDH1A1 (0.47) | ALDH1A1SIGMAR1MAPK1POLBHTT | |
| SCHEMBL235080 | 0.66 | KDM4E (0.65) | ALDH1A1SIGMAR1HSD17B10POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773456-A | EMPHYSEMA, RHEUMATOID ARTHRITIS AND PANCREATITIS | SANOFI (FR) | 1998-06-30 | — | — | US | disclosed |