SCHEMBL8701897

SCHEMBL8701897

CC(N)Cc1cc(CCC(=O)OC(C)(C)C)cc(Cc2cccnc2)c1

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 19/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8309308 0.89 TBXAS1 (0.60) TBXAS1
SCHEMBL8308276 0.87 TBXAS1 (0.49) TBXAS1
SCHEMBL8307381 0.82 TBXAS1 (0.50) TBXAS1
SCHEMBL8307374 0.82 TBXAS1 (0.48) TBXAS1
SCHEMBL8306423 0.81 TBXAS1 (0.47) TBXAS1
SCHEMBL29059890 0.80 TBXAS1 (0.51) TBXAS1
SCHEMBL8308944 0.80 TBXAS1 (0.57) TBXAS1
SCHEMBL9382024 0.78 TBXAS1 (0.43) TBXAS1
SCHEMBL8701903 0.76 TBXAS1 (0.40) TBXAS1
SCHEMBL8304942 0.75 TBXAS1 (0.54) TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5705523-A THROMBOXANE A2 SYNTHETASE INHIBITORS PFIZER INC. (US) 1998-01-06 US disclosed