Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701897 | 0.76 | TBXAS1 (0.49) | TBXAS1 | |
| SCHEMBL16178280 | 0.75 | LMNA (0.42) | L3MBTL1CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL16178281 | 0.75 | LMNA (0.42) | L3MBTL1CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL9386959 | 0.72 | TBXAS1 (0.48) | TBXAS1L3MBTL1KMT2ALMNAHPGD | |
| SCHEMBL8307374 | 0.71 | TBXAS1 (0.48) | TBXAS1L3MBTL1LTA4H | |
| SCHEMBL28300800 | 0.70 | GABBR2 (0.40) | SLC7A5 | |
| SCHEMBL9784190 | 0.69 | NAPRT (0.57) | CYP3A4LMNAHTTCYP1A2CYP2C9 | |
| SCHEMBL22035309 | 0.68 | CYP3A4 (0.46) | TBXAS1CYP3A4KMT2ALMNACYP1A2 | |
| SCHEMBL30191579 | 0.68 | CYP3A4 (0.46) | TBXAS1CYP3A4KMT2ALMNACYP1A2 | |
| SCHEMBL6243723 | 0.67 | KCNA5 (0.42) | TBXAS1L3MBTL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705523-A | THROMBOXANE A2 SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-01-06 | — | — | US | disclosed |