Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698118 | 0.87 | CYP11B1 (0.33) | ATM | |
| SCHEMBL8697941 | 0.85 | CYP11B1 (0.34) | — | |
| SCHEMBL8702189 | 0.78 | ATM (0.36) | ATM | |
| SCHEMBL8697485 | 0.73 | CYP11B1 (0.34) | — | |
| SCHEMBL8704175 | 0.65 | CYP2A6 (0.34) | — | |
| SCHEMBL8698099 | 0.65 | KCNA5 (0.36) | ATM | |
| SCHEMBL8700262 | 0.65 | CYP19A1 (0.42) | — | |
| SCHEMBL76097 | 0.60 | CYP2E1 (0.58) | — | |
| SCHEMBL8702207 | 0.59 | PIK3R1 (0.36) | — | |
| SCHEMBL8700378 | 0.58 | MAOB (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | claimed |
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |