Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704719 | 0.94 | TSHR (0.42) | MAPTHTTNPC1RAB9AHTR1A | |
| SCHEMBL8705088 | 0.94 | HSD17B10 (0.48) | MAPTHTTRAB9AHTR1AHTR1D | |
| SCHEMBL8699402 | 0.90 | KMT2A (0.49) | MAPTTSHRHSD17B10KDM4EUSP2 | |
| SCHEMBL8700061 | 0.89 | MAPT (0.57) | MAPTHTTNPC1RAB9ATSHR | |
| SCHEMBL8705064 | 0.89 | HTR1A (0.52) | MAPTHTTRAB9AHTR1AHTR1D | |
| SCHEMBL6962599 | 0.89 | KMT2A (0.39) | MAPTTSHRHSD17B10KDM4EUSP2 | |
| SCHEMBL8704931 | 0.87 | RBP4 (0.57) | MAPTHTTHTR1AHTR1DHTR1B | |
| SCHEMBL8700453 | 0.85 | RBP4 (0.56) | MAPTHTTTSHRHSD17B10KDM4E | |
| SCHEMBL8699871 | 0.85 | GAA (0.48) | MAPTTSHRHSD17B10KDM4EUSP2 | |
| SCHEMBL8703804 | 0.85 | KMT2A (0.46) | MAPTKDM4EALDH1A1GAAP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |