Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657509 | 0.86 | KMT2A (0.54) | KMT2AALDH1A1KDM4ERCE1HPGD | |
| SCHEMBL9624082 | 0.85 | KMT2A (0.59) | KMT2AALDH1A1KDM4ERCE1HPGD | |
| SCHEMBL7869937 | 0.82 | KMT2A (0.65) | KMT2AALDH1A1KDM4ERCE1HPGD | |
| SCHEMBL8889074 | 0.82 | KMT2A (0.80) | KMT2AALDH1A1KDM4ERCE1HPGD | |
| SCHEMBL9796404 | 0.80 | KDM4E (0.56) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9624375 | 0.80 | KMT2A (0.67) | KMT2AALDH1A1KDM4ERCE1HPGD | |
| SCHEMBL220059 | 0.80 | KMT2A (0.72) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1638701 | 0.79 | ALDH1A1 (0.62) | KMT2AALDH1A1KDM4ERCE1HPGD | |
| SCHEMBL8006673 | 0.79 | KMT2A (0.65) | KMT2AALDH1A1KDM4ERCE1HPGD | |
| SCHEMBL1127360 | 0.79 | KMT2A (0.65) | KMT2AALDH1A1KDM4ERCE1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998037078-A1 | SOLID PHASE AND COMBINATORIAL SYNTHESIS OF SUBSTITUTED THIOPHENES AND OF ARRAYS OF SUBSTITUTED THIOPHENES | NOVO NORDISK A/S (DK) | 1998-08-27 | — | — | WO | disclosed |