Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | CPA1 | P15085 | 2/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704879 | 0.84 | KDM4E (0.43) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| SCHEMBL8704878 | 0.81 | ALOX15 (0.38) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| SCHEMBL8668236 | 0.77 | MME (0.41) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| SCHEMBL8669966 | 0.75 | TNF (0.38) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| SCHEMBL27537229 | 0.73 | KDM4E (0.47) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| SCHEMBL7542440 | 0.73 | KDM4E (0.47) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| SCHEMBL4389856 | 0.72 | TNF (0.46) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| SCHEMBL27546548 | 0.72 | KDM4E (0.46) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| SCHEMBL8668831 | 0.71 | TNF (0.39) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| SCHEMBL6872282 | 0.69 | KDM4E (0.44) | ALOX15KDM4EMAPTTHRBNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712312-A | MELATONINERGIC RECEPTOR LIGANDS, TREATMENT OF SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1998-01-27 | — | — | US | disclosed |