Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704879 | 0.78 | KDM4E (0.43) | MMEACECPA1ACE2KDM4E | |
| SCHEMBL7362447 | 0.77 | CYP2C19 (0.60) | KDM4EMAPTALOX15THRBNFKB1 | |
| SCHEMBL7362451 | 0.77 | CYP2C19 (0.60) | KDM4EMAPTALOX15THRBNFKB1 | |
| SCHEMBL8705206 | 0.77 | ALOX15 (0.39) | MMEACECPA1ACE2KDM4E | |
| SCHEMBL5327692 | 0.76 | PKM (0.45) | KDM4EMAPTALOX15THRBNFKB1 | |
| SCHEMBL8704878 | 0.76 | ALOX15 (0.38) | MMEACECPA1ACE2KDM4E | |
| SCHEMBL8669916 | 0.74 | ALDH1A1 (0.43) | MMEACECPA1ACE2KDM4E | |
| SCHEMBL8668238 | 0.72 | TACR1 (0.43) | MMEACECPA1ACE2KDM4E | |
| SCHEMBL9450326 | 0.70 | ALDH1A1 (0.44) | KDM4EMAPTNFKB1SMN1; SMN2LTA4H | |
| SCHEMBL8187082 | 0.70 | RAB9A (0.57) | KDM4ESMN1; SMN2ALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849781-A | Tricyclic amides | ADIR ET COMPAGNIE (FR) | 1998-12-15 | — | — | US | disclosed |
| US-5712312-A | MELATONINERGIC RECEPTOR LIGANDS, TREATMENT OF SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1998-01-27 | — | — | US | disclosed |