Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4982004 | 0.82 | HPGD (0.43) | KDM4EALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL6489999 | 0.81 | — | — | |
| Zolertine SCHEMBL613371 | 0.76 | DRD2 (0.58) | SIGMAR1PARP1MAPTMEN1KMT2A | |
| Zolertine SCHEMBL611670 | 0.75 | DRD2 (0.56) | SIGMAR1PARP1MAPTMEN1KMT2A | |
| SCHEMBL18089568 | 0.72 | HRH3 (0.42) | SIGMAR1PARP1 | |
| SCHEMBL4671779 | 0.70 | — | — | |
| SCHEMBL11856358 | 0.69 | KDM4E (0.70) | KDM4EALDH1A1SIGMAR1POLBSMN1; SMN2 | |
| SCHEMBL4181784 | 0.69 | GAA (0.43) | ALDH1A1POLBSMN1; SMN2GAAMAPT | |
| SCHEMBL17002546 | 0.69 | ALOX15 (0.42) | ALDH1A1SIGMAR1 | |
| SCHEMBL1906096 | 0.68 | SIGMAR1 (0.41) | KDM4EALDH1A1SIGMAR1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773456-A | EMPHYSEMA, RHEUMATOID ARTHRITIS AND PANCREATITIS | SANOFI (FR) | 1998-06-30 | — | — | US | disclosed |