Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | ILK | Q13418 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | SDHB | P21912 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702046 | 0.86 | KDM4E (0.39) | ALDH1A1HPGDTSHRHSD17B10MAPT | |
| SCHEMBL8705953 | 0.86 | NR1I2 (0.40) | ALDH1A1HPGDTSHRHSD17B10MAPT | |
| SCHEMBL8705762 | 0.85 | SDHB (0.37) | PKMALDH1A1MAPTNR1H2NR1H3 | |
| SCHEMBL8705360 | 0.85 | MAPT (0.33) | NR3C1NR3C2ALDH1A1HSD17B10MAPT | |
| SCHEMBL8703753 | 0.85 | NR3C1 (0.33) | NR3C1NR3C2MAPTNPSR1NR1H2 | |
| SCHEMBL8706166 | 0.85 | MAPT (0.34) | NR3C1NR3C2MAPTNPSR1NR1H2 | |
| SCHEMBL8699344 | 0.84 | GAA (0.42) | ALDH1A1HPGDMAPTNPSR1PIK3CD | |
| SCHEMBL8704804 | 0.84 | MAPT (0.33) | NR3C1NR3C2ALDH1A1HPGDMAPT | |
| SCHEMBL8705210 | 0.82 | VCAM1 (0.45) | MAPTKDM4EKMT2A | |
| SCHEMBL8703808 | 0.81 | NR3C2 (0.40) | NR3C2PKMALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |