Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LIG1 | P18858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1529979 | 0.86 | DAO (0.54) | DAOPKMLIG1ALDH1A1LMNA | |
| Urea SCHEMBL4974754 | 0.79 | RAB9A (0.43) | DAOPKMALDH1A1L3MBTL1KDM4E | |
| SCHEMBL73652 | 0.76 | — | — | |
| Bromide SCHEMBL4974651 | 0.74 | — | — | |
| SCHEMBL7862009 | 0.74 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1KDM4ELMNAGLA | |
| SCHEMBL1529992 | 0.73 | NPSR1 (0.56) | DAOALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL21427036 | 0.73 | CES2 (0.46) | DAOALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL11605691 | 0.72 | CPT1B (0.47) | DAOPKMLIG1ALDH1A1KDM4E | |
| SCHEMBL2145369 | 0.71 | LMNA (0.48) | DAOALDH1A1L3MBTL1KDM4ELMNA | |
| Pyridine SCHEMBL27960280 | 0.70 | CYP2E1 (0.38) | ALDH1A1KDM4ELMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042347-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |