Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 4/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | HRH1 | P35367 | 3/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | DRD5 | P21918 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1957719 | 0.99 | TSHR (0.58) | TDP1HRH3CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL8701504 | 0.85 | DRD2 (0.58) | HRH3CYP2D6KCNH2DRD1DRD3 | |
| SCHEMBL32689498 | 0.82 | MEN1 (0.52) | HRH3CYP2D6CYP2C19DRD3KDM4E | |
| SCHEMBL32689500 | 0.81 | KDM4E (0.50) | TDP1HRH3CYP2D6CYP2C19KCNH2 | |
| SCHEMBL1031593 | 0.76 | LTA4H (0.73) | TDP1CYP2D6CYP2C19CYP1A2HSD17B10 | |
| SCHEMBL30150794 | 0.76 | LTA4H (0.73) | TDP1CYP2D6CYP2C19CYP1A2HSD17B10 | |
| SCHEMBL29573150 | 0.76 | TDP1 (0.66) | TDP1HRH3CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL2321726 | 0.76 | KDM4E (0.69) | TDP1CYP2D6CYP2C19CYP1A2HSD17B10 | |
| SCHEMBL7863482 | 0.75 | TSHR (0.67) | TDP1CYP2D6CYP2C19CYP1A2HSD17B10 | |
| SCHEMBL14397182 | 0.75 | TSHR (0.67) | TDP1CYP2D6CYP2C19CYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |