Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.43 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927272 | 0.81 | SLC9A1 (0.63) | SLC9A1SLC9A3SLC9A2MAPTKDM4E | |
| SCHEMBL8446172 | 0.80 | SLC9A1 (0.69) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8706120 | 0.78 | SLC9A1 (0.40) | SLC9A1SLC9A3SLC9A2NR1I2 | |
| SCHEMBL8706213 | 0.78 | HTT (0.47) | SLC9A1SLC9A3SLC9A2MAPTLMNA | |
| SCHEMBL6749760 | 0.75 | SLC9A1 (0.54) | SLC9A1MAPTKDM4EALDH1A1 | |
| SCHEMBL8700586 | 0.75 | SLC9A1 (0.50) | SLC9A1SLC9A3SLC9A2MAPTKDM4E | |
| SCHEMBL8705825 | 0.74 | KDM4E (0.48) | SLC9A1SLC9A3SLC9A2KDM4ETSHR | |
| SCHEMBL8580625 | 0.74 | SLC9A1 (0.45) | SLC9A1MAPTKDM4EALDH1A1 | |
| SCHEMBL1784767 | 0.73 | HCAR1 (0.41) | MAPTKDM4EALOX15TSHRMEN1 | |
| SCHEMBL8630823 | 0.73 | KDM4E (0.50) | SLC9A1SLC9A3SLC9A2KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |