Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705714 | 1.00 | PTGS2 (0.44) | PTGS2PTGS1ALDH1A1TSHRTDP1 | |
| SCHEMBL190927 | 0.88 | ALDH1A1 (0.39) | PTGS2PTGS1ALDH1A1TSHRTDP1 | |
| SCHEMBL14598537 | 0.84 | HPN (0.57) | PTGS2PTGS1ALDH1A1TSHRTDP1 | |
| SCHEMBL9504441 | 0.84 | PTGS2 (0.50) | PTGS2PTGS1ALDH1A1TSHRTDP1 | |
| SCHEMBL21241540 | 0.79 | HPN (0.47) | PTGS2PTGS1ALDH1A1TSHRTDP1 | |
| SCHEMBL14410320 | 0.78 | ALDH1A1 (0.36) | PTGS2PTGS1ALDH1A1TSHRTDP1 | |
| SCHEMBL15344011 | 0.77 | ALOX15 (0.75) | ALDH1A1ALOX15HPNMAPTSIRT5 | |
| SCHEMBL2947022 | 0.76 | PTGS2 (0.47) | PTGS2PTGS1ALDH1A1TSHRTDP1 | |
| SCHEMBL22360314 | 0.76 | CA1 (0.64) | PTGS2PTGS1ALDH1A1TSHRTDP1 | |
| SCHEMBL5857102 | 0.76 | ALDH1A1 (0.52) | PTGS2PTGS1ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482071-B1 | NEW ANTIVIRAL AGENTS | BIODOR US HOLDING CORP (US) | 1998-01-07 | — | — | EP | claimed |