Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29943719 | 0.82 | EPHX1 (0.50) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8700219 | 0.77 | MAPT (0.42) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL8699950 | 0.76 | MAPT (0.41) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL6933112 | 0.75 | ALDH1A1 (0.57) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL2060081 | 0.71 | ALDH1A1 (0.51) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL13088685 | 0.71 | ALDH1A1 (0.49) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8706114 | 0.70 | CYP1A2 (0.39) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL519468 | 0.70 | ALDH1A1 (0.52) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL5674172 | 0.69 | RAB9A (0.57) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8634915 | 0.69 | ALDH1A1 (0.55) | ALDH1A1KMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |