Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.74 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.66 |
| ▸ | CYP26B1 | Q9NR63 | 5/20 | 0.66 |
| ▸ | RARA | P10276 | 8/20 | 0.58 |
| ▸ | RARB | P10826 | 8/20 | 0.58 |
| ▸ | RARG | P13631 | 8/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8708590 | 0.87 | RARA (0.61) | RXRACYP26A1CYP26B1RARARARB | |
| SCHEMBL5894384 | 0.85 | RXRA (1.00) | RXRACYP26A1CYP26B1RARARARB | |
| SCHEMBL8101908 | 0.82 | RARB (0.72) | RXRACYP26A1CYP26B1RARARARB | |
| SCHEMBL2808583 | 0.80 | RXRA (1.00) | RXRACYP26A1CYP26B1RARARARB | |
| SCHEMBL10565430 | 0.80 | RARB (0.70) | RXRACYP26A1CYP26B1RARARARB | |
| SCHEMBL27324962 | 0.80 | RARB (0.66) | RXRACYP26A1RARARARBRARG | |
| SCHEMBL8706853 | 0.79 | RXRA (0.71) | RXRACYP26A1CYP26B1RARARARB | |
| SCHEMBL10976930 | 0.77 | RARB (0.76) | RXRACYP26A1RARARARBRARG | |
| SCHEMBL8461871 | 0.77 | RARB (0.62) | RXRACYP26A1CYP26B1RARARARB | |
| SCHEMBL10976941 | 0.77 | RARB (0.76) | RXRACYP26A1RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837725-A | Bridged bicyclic aromatic compounds and their use in modulating gene expression of retinoid receptors | SRI INTERNATIONAL (US) | 1998-11-17 | — | — | US | disclosed |