Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | EDNRA | P25101 | 2/20 | 0.38 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.37 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TCF4 | P15884 | 2/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712032 | 0.93 | SLC7A5 (0.43) | SLC7A5ADAMTS4MMP13NAMPTCYP4F2 | |
| SCHEMBL8709452 | 0.92 | SMN1; SMN2 (0.43) | SLC7A5ADAMTS4MMP13NAMPTCYP4F2 | |
| SCHEMBL8711199 | 0.91 | MRGPRX4 (0.41) | ADAMTS4MMP13EDNRAPFKFB3PFKFB4 | |
| SCHEMBL6320795 | 0.90 | EDNRA (0.39) | EDNRAITGB3ITGAV | |
| SCHEMBL8706016 | 0.89 | NPC1 (0.44) | MMP13NAMPTITGB3ITGAVMAPT | |
| SCHEMBL8705895 | 0.87 | ALDH1A1 (0.41) | NAMPTITGB3ITGAVMAPTSMN1; SMN2 | |
| SCHEMBL8709414 | 0.86 | POLB (0.41) | ADAMTS4MMP13ITGB3ITGAVSMN1; SMN2 | |
| SCHEMBL8709540 | 0.86 | ITGB3 (0.43) | ADAMTS4ITGB3ITGAV | |
| SCHEMBL8709039 | 0.86 | BCL9 (0.40) | MMP13NAMPTITGB3ITGAVCNR1 | |
| SCHEMBL8714137 | 0.85 | TARS1 (0.45) | MMP13ITGB3ITGAVMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998041515-A1 | ENDOTHOLIN RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 1998-09-24 | — | — | WO | disclosed |