Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709538 | 0.92 | NR1H4 (0.42) | SMN1; SMN2MEN1KMT2AF10PLG | |
| SCHEMBL8707231 | 0.92 | SLC7A5 (0.39) | SMN1; SMN2F10NAMPTSLC7A5MAPT | |
| SCHEMBL8712032 | 0.91 | SLC7A5 (0.43) | SMN1; SMN2MEN1KMT2ANAMPTSLC7A5 | |
| SCHEMBL8705052 | 0.91 | MEN1 (0.45) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8711019 | 0.89 | MAPT (0.43) | SMN1; SMN2MEN1KMT2ANAMPTMAPT | |
| SCHEMBL8705691 | 0.88 | MAPT (0.50) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8709132 | 0.88 | EPHX2 (0.41) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8709884 | 0.87 | MAPT (0.41) | SMN1; SMN2MEN1KMT2ANAMPTMAPT | |
| SCHEMBL8712501 | 0.87 | MAPT (0.39) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8706028 | 0.86 | MAPT (0.41) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998041515-A1 | ENDOTHOLIN RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 1998-09-24 | — | — | WO | disclosed |