Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.44 |
| ▸ | MAOB | P27338 | 7/20 | 0.44 |
| ▸ | CCR4 | P51679 | 10/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CBR1 | P16152 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27617272 | 0.71 | HSD17B3 (0.61) | MAOBTHRBKDM4EALDH1A1CYP3A4 | |
| SCHEMBL8708592 | 0.71 | KMT2A (0.64) | KDM4EALDH1A1HPGDMCL1HSD17B10 | |
| SCHEMBL8807724 | 0.64 | MAOB (0.60) | MAOBKDM4EALDH1A1CYP3A4AKR1B1 | |
| SCHEMBL15068641 | 0.61 | MAPT (0.46) | MAOACCR4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7983695 | 0.61 | PKLR (0.69) | MAOATHRBKDM4EALDH1A1CYP3A4 | |
| SCHEMBL7795084 | 0.61 | GPR35 (0.54) | THRBKDM4EALDH1A1CYP3A4AKR1B1 | |
| SCHEMBL8196371 | 0.61 | CELA1 (0.48) | MAOBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5433313 | 0.61 | MCL1 (0.54) | MAOBTHRBKDM4EALDH1A1CYP3A4 | |
| SCHEMBL11039464 | 0.61 | MAOB (0.47) | MAOBTHRBKDM4EALDH1A1CYP3A4 | |
| SCHEMBL9211053 | 0.60 | MCL1 (0.63) | MAOBTHRBKDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716983-A | ADMINISTERING PHOSPHOLIPASE INHIBITOR FOR TREATMENT OF INFLAMMATORY DISEASES, ALLERGIES, INJURIES, CARDIOVASCULAR DISORDERS, AUTOIMMUNE DISORDERS OR TRANSPLANT REJECTION | BOEHRINGER MANNHEIM GMBH (DE) | 1998-02-10 | — | — | US | claimed |