Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | CASP1 | P29466 | 3/20 | 0.59 |
| ▸ | CASP7 | P55210 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | GLA | P06280 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8706665 | 0.86 | KMT2A (0.57) | KMT2AMEN1ERAP1ALDH1A1KDM4E | |
| SCHEMBL8808673 | 0.84 | KMT2A (0.55) | KMT2AMEN1ERAP1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL8702857 | 0.82 | KMT2A (0.52) | KMT2AMEN1ERAP1ALDH1A1KDM4E | |
| Folescutol SCHEMBL554577 | 0.80 | TDP1 (0.81) | KMT2AMEN1ERAP1ALDH1A1KDM4E | |
| SCHEMBL6833560 | 0.71 | MCL1 (0.74) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL8708588 | 0.71 | MAOA (0.44) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL15836637 | 0.71 | KMT2A (1.00) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL15836700 | 0.70 | GAA (0.75) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL5433316 | 0.69 | KDM4E (0.71) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL8706801 | 0.68 | MCL1 (1.00) | KMT2AMEN1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716983-A | ADMINISTERING PHOSPHOLIPASE INHIBITOR FOR TREATMENT OF INFLAMMATORY DISEASES, ALLERGIES, INJURIES, CARDIOVASCULAR DISORDERS, AUTOIMMUNE DISORDERS OR TRANSPLANT REJECTION | BOEHRINGER MANNHEIM GMBH (DE) | 1998-02-10 | — | — | US | claimed |
| EP-0708766-B1 | USE OF COUMARINS AS PLA 2-INHIBITORS, NEW COUMARINS, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-10 | — | — | EP | claimed |