Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 9/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840512 | 0.87 | KCNA3 (0.38) | TRPM8KCNA3ALDH1A1KDM4EMEN1 | |
| SCHEMBL8840576 | 0.81 | TRPM8 (0.32) | TRPM8 | |
| SCHEMBL9033513 | 0.78 | KCNA3 (0.41) | TRPM8KCNA3ALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL8704982 | 0.77 | KCNA3 (0.40) | TRPM8KCNA3ALDH1A1KDM4EMEN1 | |
| SCHEMBL8840550 | 0.74 | L3MBTL1 (0.35) | KMT2A | |
| SCHEMBL8840549 | 0.73 | ALDH1A1 (0.37) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL9040850 | 0.73 | NPC1 (0.42) | TRPM8ALDH1A1MEN1CYP3A4KMT2A | |
| SCHEMBL8840443 | 0.73 | L3MBTL1 (0.33) | — | |
| SCHEMBL8840520 | 0.72 | NPC1 (0.41) | TRPM8ALDH1A1MEN1CYP3A4KMT2A | |
| SCHEMBL8840449 | 0.71 | OPRM1 (0.31) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0719255-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007890-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |