Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | EPOR | P19235 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 4/20 | 0.31 |
| ▸ | NOS1 | P29475 | 3/20 | 0.31 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714819 | 0.80 | CPB2 (0.43) | CPB2GSRRNPEPNOS2NOS1 | |
| SCHEMBL468723 | 0.76 | CPB2 (0.47) | CPB2GSRRNPEPBLM | |
| SCHEMBL468721 | 0.76 | CPB2 (0.47) | CPB2GSRRNPEPBLM | |
| SCHEMBL8821909 | 0.76 | CPB2 (0.38) | CPB2GSRRNPEPEPOR | |
| SCHEMBL8707562 | 0.73 | CPB2 (0.45) | CPB2GSRRNPEPEPORNOS2 | |
| SCHEMBL28480205 | 0.71 | CPB2 (0.41) | CPB2GSRRNPEPCYP1A2TSHR | |
| SCHEMBL29483412 | 0.71 | CPB2 (0.41) | CPB2GSRRNPEPCYP1A2TSHR | |
| SCHEMBL11015274 | 0.71 | CPB2 (0.41) | CPB2GSRRNPEPCYP1A2TSHR | |
| SCHEMBL7901279 | 0.70 | NOS2 (0.46) | GSRNOS2NOS1NOS3CYP1A2 | |
| SCHEMBL7901280 | 0.70 | NOS2 (0.46) | GSRNOS2NOS1NOS3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885188-A1 | HYDROXYAMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997032844-A1 | HYDROXYAMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-09-12 | — | — | WO | disclosed |