Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.35 |
| ▸ | GAA | P10253 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584346 | 0.82 | KMT2A (0.37) | KMT2AGAAALDH1A1MAPTTDP1 | |
| SCHEMBL8583282 | 0.82 | PTPN1 (0.33) | — | |
| SCHEMBL8709022 | 0.78 | FABP4 (0.34) | KMT2AGAAALDH1A1MAPTTDP1 | |
| SCHEMBL8310604 | 0.74 | MAPT (0.56) | KMT2AGAAALDH1A1MAPTTDP1 | |
| SCHEMBL8310599 | 0.74 | MAPT (0.56) | KMT2AGAAALDH1A1MAPTTDP1 | |
| SCHEMBL8991958 | 0.72 | KMT2A (0.46) | KMT2AGAAALDH1A1MAPTTDP1 | |
| SCHEMBL8933459 | 0.72 | KMT2A (0.46) | KMT2AGAAALDH1A1MAPTTDP1 | |
| SCHEMBL8986231 | 0.72 | KMT2A (0.46) | KMT2AGAAALDH1A1MAPTTDP1 | |
| SCHEMBL8309496 | 0.71 | FABP4 (0.55) | KMT2AGAAMAPTMEN1POLB | |
| SCHEMBL20006030 | 0.70 | ALDH1A1 (0.42) | KMT2AGAAALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716975-A | NONTOXIC RHODANINE DERIVATIVES; ANTIDIABETIC AGENTS, CATHEPSIN D INHIBITORS, B-AMYLOID PROTEIN REDUCTION | ELI LILLY AND COMPANY (US) | 1998-02-10 | — | — | US | disclosed |