Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709018 | 0.82 | KMT2A (0.35) | — | |
| SCHEMBL8582964 | 0.81 | PTGS2 (0.39) | PTGS2 | |
| SCHEMBL8579119 | 0.77 | CYP1A2 (0.40) | PTGS2 | |
| SCHEMBL8583284 | 0.77 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL8583061 | 0.72 | HSPA5 (0.32) | PTGS2 | |
| SCHEMBL14853306 | 0.71 | HSP90AA1 (0.46) | PTPN1PTGS2 | |
| SCHEMBL8708475 | 0.70 | PTGS2 (0.40) | PTGS2 | |
| SCHEMBL8911876 | 0.69 | CA2 (0.39) | PTGS2 | |
| SCHEMBL8306585 | 0.68 | PTGS2 (0.69) | PTGS2 | |
| SCHEMBL8306587 | 0.68 | PTGS2 (0.69) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731336-A | USING ARYL-SUBSTITUTED RHODAMINES | ELI LILLY AND COMPANY (US) | 1998-03-24 | — | — | US | disclosed |
| US-5716975-A | NONTOXIC RHODANINE DERIVATIVES; ANTIDIABETIC AGENTS, CATHEPSIN D INHIBITORS, B-AMYLOID PROTEIN REDUCTION | ELI LILLY AND COMPANY (US) | 1998-02-10 | — | — | US | disclosed |