Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | EEF2K | O00418 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712035 | 0.91 | EDNRA (0.39) | LSSITGB3ITGAVACACBCYP19A1 | |
| SCHEMBL8709132 | 0.90 | EPHX2 (0.41) | EPHX2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8705303 | 0.89 | MAPT (0.40) | EPHX2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8709894 | 0.88 | FLT1 (0.44) | EPHX2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8705691 | 0.88 | MAPT (0.50) | EPHX2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8710102 | 0.88 | EPHX2 (0.42) | EPHX2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8709556 | 0.87 | MEN1 (0.43) | EPHX2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8705052 | 0.86 | MEN1 (0.45) | EPHX2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8709789 | 0.84 | MEN1 (0.39) | EPHX2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8709625 | 0.84 | NLRP3 (0.43) | EPHX2ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998041515-A1 | ENDOTHOLIN RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 1998-09-24 | — | — | WO | disclosed |