Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705645 | 0.93 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8712259 | 0.91 | BMP1 (0.43) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8709132 | 0.91 | EPHX2 (0.41) | MEN1KMT2ASMN1; SMN2MAPTGAA | |
| SCHEMBL8711019 | 0.91 | MAPT (0.43) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8709789 | 0.91 | MEN1 (0.39) | MEN1KMT2ASMN1; SMN2MAPTEPHX2 | |
| SCHEMBL8705052 | 0.90 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2MAPTGAA | |
| SCHEMBL8705303 | 0.90 | MAPT (0.40) | MEN1KMT2ASMN1; SMN2MAPTGAA | |
| SCHEMBL8709894 | 0.89 | FLT1 (0.44) | MEN1KMT2ASMN1; SMN2MAPTEGFR | |
| SCHEMBL8705691 | 0.89 | MAPT (0.50) | MEN1KMT2ASMN1; SMN2MAPTGAA | |
| SCHEMBL8710102 | 0.88 | EPHX2 (0.42) | MEN1KMT2ASMN1; SMN2MAPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998041515-A1 | ENDOTHOLIN RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 1998-09-24 | — | — | WO | disclosed |