Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709207 | 1.00 | ALOX15 (0.42) | ALOX15HTTAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL1325516 | 0.84 | MEN1 (0.43) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL995191 | 0.84 | MEN1 (0.43) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL1325515 | 0.84 | MEN1 (0.43) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL17186108 | 0.81 | HTT (0.49) | ALOX15HTTALDH1A1PABPC1PLK1 | |
| SCHEMBL6041219 | 0.78 | MEN1 (0.40) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9382586 | 0.77 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2LMNACYP3A4MEN1 | |
| SCHEMBL642839 | 0.77 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2LMNACYP3A4MEN1 | |
| SCHEMBL7156656 | 0.77 | HTT (0.39) | HTTALDH1A1LMNACYP3A4MEN1 | |
| SCHEMBL31048871 | 0.77 | HTT (0.39) | HTTALDH1A1LMNACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788360-A4 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES | PROSCRIPT INC (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0788360-A1 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES | PROSCRIPT, INC. (US) | 1997-08-13 | — | — | EP | disclosed |