Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995191 | 0.93 | MEN1 (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL1325515 | 0.93 | MEN1 (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL1325516 | 0.93 | MEN1 (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL6139041 | 0.81 | MEN1 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL27597529 | 0.81 | MEN1 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL8507676 | 0.80 | SMN1; SMN2 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2GABRB1 | |
| SCHEMBL8709208 | 0.78 | ALOX15 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL8709207 | 0.78 | ALOX15 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL9382586 | 0.78 | SMN1; SMN2 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL642839 | 0.78 | SMN1; SMN2 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060063807-A1 | Low molecular weight peptidomimetic growth hormone secretagogues | GENENTECH, INC. (US) | 2006-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063807-A1 | Low molecular weight peptidomimetic growth hormone secretagogues | GHSR, GHRHR, IGFBP1 | MEN1 269/4885KMT2A 2850/4885ALDH1A1 4643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.