Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 7/20 | 0.56 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769019 | 0.90 | TAS2R14 (0.58) | TAS2R14CNR2CA12CA1CA2 | |
| SCHEMBL17030819 | 0.85 | CNR2 (0.64) | TAS2R14CNR2POLB | |
| SCHEMBL11722886 | 0.82 | CNR2 (0.55) | TAS2R14CNR2CA12CA1CA2 | |
| SCHEMBL9623455 | 0.79 | CNR2 (0.53) | TAS2R14CNR2CA12CA1CA2 | |
| SCHEMBL16636846 | 0.77 | CNR2 (0.51) | CNR2CA12CA1CA2CA4 | |
| SCHEMBL22451561 | 0.77 | TAS2R14 (0.64) | TAS2R14CNR2CA12CA1CA2 | |
| SCHEMBL6121647 | 0.76 | TAS2R14 (0.79) | TAS2R14CNR2CA12CA1CA2 | |
| SCHEMBL11497159 | 0.75 | CNR2 (0.63) | TAS2R14CNR2ALDH1A1POLBMAPT | |
| SCHEMBL20379430 | 0.74 | LMNA (0.47) | TAS2R14CNR2ALDH1A1POLBCXCR3 | |
| SCHEMBL12205672 | 0.73 | CNR2 (0.56) | TAS2R14CNR2POLBMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646119-B1 | QUATERNARY NITROGEN-CONTAINING PHOSPHONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM AS WELL AS DENTAL CALCULUS AND PLAQUE | PROCTER & GAMBLE PHARMA (US) | 1998-07-15 | — | — | EP | disclosed |
| EP-0849272-A1 | Quaternary nitrogen-containing phosphonate compounds for treating abnormal calcium and phosphate metabolism as well as dental calculus and plaque | Procter & Gamble Pharmaceuticals, Inc. (US) | 1998-06-24 | — | — | EP | disclosed |
| US-5770586-A | Quaternary nitrogen-containing phosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism amd methods of treating and preventing dental calculus and plaque | THE PROCTER & GAMBLE COMPANY (US) | 1998-06-23 | — | — | US | disclosed |
| US-5763611-A | TREATING OSTEOPOROSIS, RHEUMATOID ARTHRITIS | THE PROCTER & GAMBLE COMPANY (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0646119-A1 | QUATERNARY NITROGEN-CONTAINING PHOSPHONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM AS WELL AS DENTAL CALCULUS AND PLAQUE | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1995-04-05 | — | — | EP | disclosed |
| EP-0642520-A1 | THIO-SUBSTITUTED CYCLIC PHOSPHONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS (US) | 1995-03-15 | — | — | EP | disclosed |
| US-5391743-A | Treating osteoporosis, rheumatoid arthritis, osteoarthritis | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1995-02-21 | — | — | US | disclosed |
| WO-1993024498-A1 | QUATERNARY NITROGEN-CONTAINING PHOSPHONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM AS WELL AS DENTAL CALCULUS AND PLAQUE | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1993-12-09 | — | — | WO | disclosed |
| WO-1993024497-A1 | THIO-SUBSTITUTED CYCLIC PHOSPHONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1993-12-09 | — | — | WO | disclosed |