SCHEMBL22451561

SCHEMBL22451561

COc1cccc(CN(CCC(=O)O)S(=O)(=O)c2ccc(C)cc2)c1

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TAS2R14 Q9NYV8 7/20 0.64
CA12 O43570 4/20 0.61
CA1 P00915 4/20 0.61
CA2 P00918 4/20 0.61
CA4 P22748 4/20 0.61
CA9 Q16790 4/20 0.61
BMP1 P13497 2/20 0.59
MEN1 O00255 1/20 0.54
HTT P42858 1/20 0.54
KMT2A Q03164 1/20 0.54
CNR2 P34972 1/20 0.53
MEP1B Q16820 2/20 0.53
ADAM10 O14672 1/20 0.53
MMP2 P08253 1/20 0.53
MMP9 P14780 1/20 0.53
MMP13 P45452 1/20 0.53
ADAM17 P78536 1/20 0.53
MEP1A Q16819 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7814402 0.84 CNR2 (0.72) TAS2R14BMP1MEN1HTTKMT2A
SCHEMBL16793676 0.84 KMT2A (0.75) TAS2R14CA12CA1CA2CA4
SCHEMBL29676548 0.84 KMT2A (0.75) TAS2R14CA12CA1CA2CA4
SCHEMBL7343981 0.83 BMP1 (0.77) TAS2R14BMP1CNR2MEP1B
SCHEMBL3397090 0.82 ALDH1A1 (0.62) TAS2R14CA12CA1CA2CA4
SCHEMBL25489461 0.80 KMT2A (0.62) TAS2R14CA12CA1CA2CA4
SCHEMBL6769019 0.80 TAS2R14 (0.58) TAS2R14CA12CA1CA2CA4
SCHEMBL6121647 0.79 TAS2R14 (0.79) TAS2R14CA12CA1CA2CA4
SCHEMBL1615504 0.79 TAS2R14 (1.00) TAS2R14
SCHEMBL1278600 0.78 TAS2R14 (1.00) TAS2R14MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200299306-A1 COMPOUNDS WITH A BENZO[A]CARBAZOLE STRUCTURE AND USE THEREOF UNIVERSITA' DI PISA (IT) 2020-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200299306-A1 COMPOUNDS WITH A BENZO[A]CARBAZOLE STRUCTURE AND USE THEREOF MKI67, CCNI, CASP3 TAS2R14 3613/4885CA12 1254/4885CA1 1913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.