Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628785 | 0.94 | TSHR (0.56) | TSHRLMNAGAAMEN1KMT2A | |
| Terephthalamide SCHEMBL27950892 | 0.83 | TSHR (1.00) | TSHRLMNAGAAPOLBCES1 | |
| SCHEMBL260727 | 0.83 | TSHR (1.00) | TSHRLMNAGAAPOLBCES1 | |
| Hydrochloric Acid SCHEMBL11203029 | 0.81 | TSHR (0.96) | TSHRLMNAGAACES1CA1 | |
| Methyl Alcohol SCHEMBL27858599 | 0.79 | TSHR (0.92) | TSHRLMNAGAACES1CA1 | |
| Hydrochloric Acid SCHEMBL27509957 | 0.79 | TSHR (0.92) | TSHRLMNAGAAPOLBCES1 | |
| SCHEMBL5696165 | 0.78 | TSHR (0.88) | TSHRLMNAGAAPOLBCES1 | |
| SCHEMBL10936559 | 0.77 | MPO (0.44) | LMNAGAAMEN1KMT2APOLB | |
| SCHEMBL11426817 | 0.77 | ALDH1A1 (0.56) | TSHRGAAMEN1KMT2APOLB | |
| SCHEMBL5466293 | 0.77 | TSHR (0.79) | TSHRLMNAGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042347-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |