Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709646 | 0.94 | TSHR (0.69) | TSHRMEN1KMT2APOLBCES1 | |
| SCHEMBL10936559 | 0.82 | MPO (0.44) | MEN1KMT2APOLBCA1CA2 | |
| SCHEMBL11426817 | 0.82 | ALDH1A1 (0.56) | TSHRMEN1KMT2APOLBCES1 | |
| SCHEMBL8706944 | 0.80 | KMT2A (0.63) | TSHRMEN1KMT2APOLBCES1 | |
| SCHEMBL165760 | 0.79 | TSHR (0.62) | TSHRMEN1KMT2APOLBCES1 | |
| SCHEMBL28723007 | 0.79 | MEN1 (0.82) | TSHRMEN1KMT2APOLBCES1 | |
| SCHEMBL27815181 | 0.79 | MAPT (0.67) | TSHRMEN1KMT2APOLBCES1 | |
| SCHEMBL296991 | 0.77 | MEN1 (0.68) | TSHRMEN1KMT2APOLBCES1 | |
| SCHEMBL10932097 | 0.77 | KMT2A (0.44) | TSHRMEN1KMT2ACES1CA1 | |
| SCHEMBL9592831 | 0.76 | TSHR (0.63) | TSHRMEN1KMT2APOLBCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182881-A | N-[Diaminophosphinyl]arylcarboxamides | MORTON-NORWICH PRODUCTS, INC. (US) | 1980-01-08 | — | — | US | claimed |
| US-5840917-A | ADMINISTERING TO MAMMAL TO ERADICATE HELICOBACTER PYLORI | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| WO-1998042347-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |
| EP-0852498-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-07-15 | — | — | EP | disclosed |
| WO-1997011705-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |
| US-4182881-A | N-[Diaminophosphinyl]arylcarboxamides | MORTON-NORWICH PRODUCTS, INC. (US) | 1980-01-08 | — | — | US | disclosed |